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merged with his instrument company to form the American Cystoscope Makers Inc. This company was incorporated in 1900 and became and remained the dominant developer and manufacturer of endoscopic instruments for the United States for more than half a century. The first American-made and designed instrument was produced by Wappler in 1902; shortly thereafter he developed a new telescopic objective lens embodying a hemispherical lens, with William K. Otis, for which he was granted his first U.S. patent.

In 1929, he was elected an honorary member of the AUA. Wappler died in 1932.

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